Cryosurgery is an advanced freezing innovation that is fast, effective, and safe for the removal of benign skin lesions on the face and body. 

CryoPen® Cryosurgery device delivers an ultra-cold jet of high-pressure nitrous oxide directly on to skin lesions. The nitrous oxide destroys the tissue by freezing the intercellular fluid and forming ice shards that rupture the cell’s membrane, destroying the cells. The ultra-cold nitrous oxide cuts off the blood supply during the freezing process, ensuring the client’s safety during the process.

Treatment method

First Freeze Cycle

The clinician will hold the applicator as close as possible to the lesion, and move it quickly towards and away from it. Depending on the lesion size and depth, the treatment could be 1 to 30 seconds.


After the first freezing cycle, the tissue will be allowed to thaw for about 30 seconds.

Second Freeze Cycle

The second freeze cycle will start. The tissue will freeze faster than during the first freezing cycle.

CryoPen® Cryotherapy can treat all common benign skin lesions including age spots, warts, skin tags, verruca’s, cherry angiomas and many more.


From £60 per treatment

1 treatment covers:

  • Warts
  • Varrucae’s
  • Age Spots
  • Cherry Angiomas
  • Small Skin Tags
  • Milia etc

Book your consultation

A consultation is required before your appointment. You may be referred back to your local GP for more complex lesions

We look forward to helping you regain skin confidence with our CryoPen treatment at Rejuven8.

Frequently asked questions

How safe is cryotherapy?

Cryotherapy is a relatively low-risk procedure. CryoPen® delivers N2O directly to the lesion, and not the healthy surrounding tissue. CryoPen® is both CE and FDA registered.

How long are CryoPen® treatments?

The penetration rate of freezing with the CryoPen® is approximately 1mm per 5 seconds, with a maximum freezing depth of 3 to 6mm depending on the used applicator. The duration of the treatment time will depend on the surface area and the thickness of the tissue being treated. Upon the clinical evaluation of the thickness of the lesion, the operator will choose an application time from 1 to 30 seconds.

Is the treatment painful?

There will be a pain sensation similar to a ballpoint pen being pushed onto the skin when the nitrous oxide reaches the bottom of the lesion. There might be a little residual stinging for a few minutes after treatment. Occasionally a blister might form and persist for a few hours.

Will there be a follow up session?

A follow up visit is recommended after 2 to 4 weeks to confirm that all pathological tissue has disappeared or if a follow up treatment is necessary.

What if I have darker skin?

Repeated short freezing cycles of 3 to 6 seconds at two-week intervals are recommended if you have a darker skin type.

Are there any side effects?

CryoPen® Therapy is relatively low risk. There are a few side effects that may occur as a result of treatment, including:

•Pigmentary changes (hypopigmentation and hyperpigmentation)

•Shards of ice (minor shards of frozen ice may blow out, that will thaw on contact with healthy skin)

•Hair follicle damage and permanent alopecia

(Especially when treating lesions on sites with coarse terminal hair)

•Discuss any concerns with your clinician